Leaders in the world’s digital twin sector are coming together from Australia, the United Kingdom, and Canada to engage and collaborate by sharing their thought leadership on the digital twin revolution. Digital Twinning is a vast domain with broad applications and it is by nature multidisciplinary. It enables the next generation of analysis interconnecting various systems with a high degree of complexity. It benefits from historical, concurrent, and predictive analytics, as well as numerous subfields of simulation. It also benefits from a variety of scientific fields as its core components but also as part of the phenomena the Digital Twin aims to simulate. Hence, paper submissions from all allied disciplines are welcome.